Jon Hamilton

Scientists have taken a small step toward personalizing treatment for depression.

A study of more than 300 people with major depression found that brain wave patterns predicted which ones were most likely to respond to the drug sertraline (Zoloft), a team reported Monday in the journal Nature Biotechnology.

If the approach pans out, it could offer better care for the millions of people in the U.S. with major depression.

Scientists have found a clue to how autism spectrum disorder disrupts the brain's information highways.

The problem involves cells that help keep the traffic of signals moving smoothly through brain circuits, a team reported Monday in the journal Nature Neuroscience.

The team found that in both mouse and human brains affected by autism, there's an abnormality in cells that produce a substance called myelin.

Brain organoids, often called "minibrains," have changed the way scientists study human brain development and disorders like autism.

But the cells in these organoids differ from those in an actual brain in some important ways, scientists reported Wednesday in the journal Nature.

In early December at the Kennedy Space Center in Florida, two anxious scientists were about to send 20 years of research into orbit.

"I feel like our heart and soul is going up in that thing," Dr. Emily Germain-Lee told her husband, Dr. Se-Jin Lee, as they waited arm-in-arm for a SpaceX rocket to launch.

Black and Hispanic Americans are especially vulnerable to Alzheimer's disease. Yet they're often underrepresented in scientific studies of the disease.

So on a cool Sunday morning in Cleveland, two research associates from Case Western Reserve University's School of Medicine have set up an information table at a fundraising walk organized by the local chapter of the Alzheimer's Association.

"We are looking for families, minorities and people with early onset," Leah Cummings tells passersby who are waiting for the walk to begin.

A leukemia drug may have cleared another hurdle as a potential treatment for Parkinson's disease.

But critics say it's still not clear whether the drug, nilotinib (brand name Tasigna), is truly safe or effective for this use.

When Matthew Braun gets out of medical school, he'll be able to prescribe opioids.

A decade ago, he was addicted to them.

"The first time I ever used an opioid, I felt the most confident and powerful I'd ever felt," Braun says. "So I said, 'This is it. I want to do this the rest of my life.' "

Opioids took away his anxiety, his inhibitions, his depression. And they were easy to get.

"I just started breaking into houses," Braun says. "I found it amazing how trusting people were in leaving windows open and doors unlocked, and I found a lot of prescriptions."

When we hear a sentence, or a line of poetry, our brains automatically transform the stream of sound into a sequence of syllables.

But scientists haven't been sure exactly how the brain does this.

Now, researchers from the University of California, San Francisco, think they've figured it out. The key is detecting a rapid increase in volume that occurs at the beginning of a vowel sound, they report Wednesday in Science Advances.

When Sepiedeh Keshavarzi was getting her medical degree in Tehran, she often read research papers by prominent scientists in the U.S.

"It was my dream at some point when I was much younger to do research in the States," she says.

Not anymore.