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In the NoCo

Treating postpartum depression with psychedelics? Why researchers say it may be effective

A woman sits in a dark room cross-legged on a bed
Photo by Ben Blennerhassett
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Unsplash

Nearly one in five new moms experiences anxiety or depression during pregnancy or after giving birth. These conditions can lead to difficulty bonding with a newborn, or a higher risk of suicide, if left untreated.

But a new experimental treatment is giving some researchers hope. It's a psychoactive substance derived from mushrooms called luvesilocin.

In a recent set of FDA trials, a single dose of luvesilocin turned out to be highly effective – and worked more quickly – in improving patients' postpartum depression and anxiety.

Dr. Camille Hoffman is an OB-GYN and Professor of Maternal Fetal Medicine at the University of Colorado Anschutz. She helped oversee an early clinical study of luvesilocin, and wrote about it for The Conversation.

Hoffman spoke with Erin O'Toole about what researchers found, and why luvesilocin may be a promising alternative to psychotherapy or prescription drugs that are often used to treat postpartum depression.

KUNC's In The NoCo is a daily slice of stories, news, people and issues. It's a window to the communities along the Colorado Rocky Mountains. The show brings context and insight to the stories of the day, often elevating unheard voices in the process. And because life in Northern Colorado is a balance of work and play, we celebrate the lighter side of things here, too.
As the host of KUNC’s news program and podcast In The NoCo, I work closely with our producers and reporters to bring context and diverse perspectives to the important issues of the day. Northern Colorado is such a diverse and growing region, brimming with history, culture, music, education, civic engagement, and amazing outdoor recreation. I love finding the stories and voices that reflect what makes NoCo such an extraordinary place to live.
Brad Turner is an executive producer in KUNC's newsroom. He manages the podcast team that makes In The NoCo, which also airs weekdays in Morning Edition and All Things Considered. His work as a podcaster and journalist has appeared on NPR's Weekend Edition, NPR Music, the PBS Newshour, Colorado Public Radio, MTV Online, the Denver Post, Boulder's Daily Camera, and the Longmont Times-Call.